Biochemistry meeting, Marrakech. Speakers: Speakers coming from Morocco and different countries, ...
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PREVIOUS MANIFESTATIONS
CONGRESS 2002 (CASABLANCA)
CONGRESS 2004 (MARRAKECH)
CONGRESS 2006 (AGADIR)
SEBBM |
Full
Professor; Head of the Structural Proteomics Laboratory. Instituto
de Biomedicina de Valencia, C.S.I.C., Jaime Roig 11, Lecture Title: 'Snake venomics and antivenomics: from ophidian evolution to biomedicine' |
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1998-
Staff Researcher at Researcher at Instituto de Biomedicina, 1993-98:
Staff Researcher at Veterinary Highschool, Hannover (Ger) (Structural
Biology) PROFESSIONAL
POSITIONS PUBLICATIONS (Selected publications from the last 5 years, out of 260 papers in peer-reviewed journals and book chapters since 1986)
Obtustatin, a potent and selective inhibitor of 1 1 integrin in
vitro and angiogenesis in vivo NMR solution structure of the non-RGD disintegrin obtustatin. Moreno-Murciano, M.P., Monleón, D., Marcinkiewicz, C., Calvete, J.J. & Celda, B. J. Mol. Biol. 329 (2003) 135-145 Snake venom disintegrins. Novel dimeric disintegrins and structural diversification by disulphide bond engineering. Calvete, J.J., Moreno-Murciano, M.P., Theakston, R.D.G., Kisiel, D.G. & Marcinkiewicz, C. Biochem. J. 372 (2003) 725-734 Concerted motions of the integrin-binding loop and the C-terminal tail of the non-RGD disintegrin obtustatin. Monleón, D., Moreno-Murciano, M.P., Kovacs, H., Marcinkiewicz, C., Calvete, J.J. & Celda, B. J. Biol. Chem. 278 (2003) 45570-45576 Snake venomics: characterization of protein families in Sistrurus barbouri venom by cysteine mapping, N-terminal sequencing, and MS/MS analysis. Juárez, P., Sanz,L. & Calvete, J.J. Proteomics 4 (2004) 327-338 Structural
requirements of MLD-containing disintegrins for distinct inhibition
of 4 and 9 integrins Conformation and concerted dynamics of the integrin binding site and the C-terminal region of echistatin revealed by homonuclear NMR. Monleón, D., Esteve, V., Kovacs, H., Calvete, J.J. & Celda, B. Biochem. J. 387 (2005) 57-66 Structure-function correlations of snake venom disintegrins. Calvete, J.J. Curr. Pharm. Design 11 (2005) 829-835 Snake venomics: comparative analysis of the venom proteomes of the Tunisian snakes Cerastes cerastes, Cerastes vipera and Macrovipera lebetina. Bazaa, A., Marrakchi, N., El Ayeb, M., Sanz, L. & Calvete, J.J.Proteomics 5 (2005) 4223-4235 The
first crystal structure of a Mimosoideae lectin reveals a novel
quaternary arrangement of a widespread domain. Gallego del Sol,
F., Nagano, C.S., Cavada, B.S. & Calvete, J.J. cDNA
cloning and functional expression of jerdostatin, a novel RTS-disintegrin
from Trimeresurus jerdonii and a specific inhibitor of the 1 1
integrin Conformational
diversity of the Goodpasture antigen, the noncollagenous-1 domain
of the 3 chain of collagen IV. Calvete, J.J., Revert, F., Blanco,
M., Cervera, J., Tárrega, C., Sanz, L., Revert-Ros, F.,
Granero, F., Pérez-Payá, E., Hudson, B.G. &
Saus, J. Molecular cloning of disintegrins from Cerastes vipera and Macrovipera lebetina transmediterranea venom gland cDNA libraries. Insight into the evolution of the snake venom´s integrin inhibition system. Sanz, L., Bazaa, A., Marrakchi, N., Pérez, A., Chenik, M., Bel Lasfer, Z., El Ayeb, M. & Calvete, J.J., Biochem. J. 395 (2006) 385-392 Characterizing
the tick carboxypeptidase inhibitor: Molecular basis for its two-domain
nature Venom
proteomes of closely-related Sistrurus rattlesnakes with divergent
diets Snake
venomics of Bitis gabonica gabonica. Protein family composition,
subunit organization of venom toxins, and characterization of
dimeric disintegrins bitisgabonin-1 and bitisgabonin-2 KTS- and RTS-disintegrins: anti-angiogenic viper venom peptides specifically targeting the 1 1 integrin Calvete, J.J., Marcinkiewicz, C. & Sanz, L. Curr. Pharm. Des. 13 (2007) 2853-2859 Snake venomics. Protocols and applications. Calvete, J.J., Juárez, P. & Sanz, L.J. Mass Spectrom. 42 (2007) 1405-1414 Snake
venomics of Bitis species reveals large intragenus venom toxin
composition variation. Application to taxonomy of congeneric taxa.
Calvete, J.J., Escolano, J. & Sanz, L. Insights
into the structural basis of the pH-dependent dimer-tetramer equilibrium
through crystallographic analysis of recombinant Diocleinae lectins.
Nagano, C.S., Calvete, J.J., Barettino, D., Pérez, A.,
Cavada, B.S. & Sanz, L. Snake venomics of Central American pitvipers. Clues for rationalizing the distinct envenomation profiles of Atropoides nummifer and Atropoides picadoi. Angulo, Y., Escolano, J., Lomonte, B., Gutiérrez, J.M., Sanz, L. & Calvete, J.J. J. Proteome Res. 7 (2008) 708-719 Snake
venomics of the South and Central American Bushmasters. Comparison
of the toxin composition of Lachesis muta gathered from proteomic
versus transcriptomic analysis
CURRENT RESEARCH INTEREST Memberships
in Professional Societies REVIEWER
OF GRANT APPLICATIONS FOR:
MEMBER OF EDITORIAL BOARDS: |
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Department
of Biomedical Technology Lecture Title: 'Oxidative stress; sicklecell syndrome as model' ![]() |
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EDUCATION: 1. PhD (Biochemistry, 1993) University of Port-Harcourt, Nigeria. Dissertation on "Blood Redox Changes in Sickle Cell Disease" 2. Post-graduate studies in Medicinal Chemistry, University of Houston, Texas (1978-79). 3. MSc (Chemistry, 1978) Youngstown State University, Ohio. 4. BSc (Biology/Chemistry, 1975) Indiana University of Pennsylvania, Indiana Pennsylvania (Norah E Zink University Scholar, 1972-1975). MEMBERSHIP OF PROFESSIONAL ASSOCIATIONS: 1. Fellow, Institute of Chartered Chemists of Nigeria (FICCON) 2. Member, Science Teachers Association of Nigeria (STAN) 3. Member, Nigerian Society of Biochemistry and Molecular Biology (NSBMB). 4. Member, Chemical Society of Nigeria (C.S.N). 5. Associate Member, Nigerian Institute for Biomedical Engineering (NIBES). AREAS OF CURRENT RESEARCH INTEREST. 1. Investigation into the Bioenergetics/Redox aspects of Diseases; Sicklecell, Diabetes, Redox stress, Malaria, HIV?AIDS, etc. 2. Investigation into the relationship of structure and function in blood and other biological systems. 3. Studies on the chemistry of African traditional herbs/foods. 4. Investigation into the kinetic molecular origin of natural constants (Epsilon, Pi and Feigenbaum's number) 5. Studies on African Cosmology/indigenous Knowledge system in relation to Science. PUBLICATIONS. Have published sizable journal articles/books in Chemistry/Biochemistry/Systems' modeling, and African Cosmology. SPECIAL RECOGNITION 1. Listed by Philosopedia (see Chidi Gideon Osuagwu at www.philosopedia.org). 2. Nomination to UNESCO in 2005 by the Imo State Government as a "Living Human Treasure" for work in African Cosmology (see www.unescong.org/Living Human Treasures). JOB EXPERIENCE: 1. Currently, Senior Lecturer (Biochemistry), School of Health Technology, Federal University of Technology, Owerri, Nigeria. Have taught, since 1978, in different higher institutions in the United States and Nigeria. CURRENT CIVIC/ADMINISTRATIVE RESPONSIBILITIES: 1. Member, Board of Directors, Alvana Community Bank (2001-date) 2. Member, Scientific Council, Whelan Research Academy, Owerri, Nigeria. 3. Head, Department of Biomedical Technology, Federal University of Technology, Owerri, Nigeria. |
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Scientific
Director-Lecturer Lecture Title: 'Prion: a splendid and fatal molecular machine' ![]() |
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Current
position: Since 2002 Research Scientist and Scientific Director
at the Department of Human Histology- Centre of Research on Prion
Protein "CRPP". University of Liège, Belgium.
EDUCATIONAL BACKGROUND: 1994-1999
Ph.D. in Biochemistry, University of Liège, Belgium. EMPLOYMENT HISTORY: 2002-
Present: Scientifc Director, Centre of Research on Prions Proteins,
University of Liège 1 Ingrid Dupiereux, Willy Zorzi, Olivier Thellin, Olivier Pierard, Nicole Watt, NM Hooper, Ernst Heinen and Benaïssa ELMoualij. Potent protective effect of prion proteins on paraquat-induced mitochondrial uncoupling in Human Neuroblstoma SH-SY5Y cells. Journal of neurosciences research, 2008 86:653-659. 2 Dupiereux I, Zorzi W, Danièle Zorzi, Rachidi Walid, Bernard Lheureux, Heinen E, Elmoualij B. Study on the toxic mechanism of prion protein peptide 106-126 in neuronal and non neuronal cells J Neurosci Res. 2006 Aug 15;84(3):637-46. 3 Falisse-Poirrier N, Ruelle V, Elmoualij B, Zorzi D, Pierard O, Heinen E, De Pauw E, Zorzi W. Advances in immunoproteomics for serological characterization of microbial antigens. J Microbiol Methods. 2006 Dec;67(3):593-6. Epub 2006 Jul 5. 4
Dupiereux I, Zorzi W, Lins L, Brasseur R, Colson P, Heinen E,
ElMoualij B. 5 Stéphanie GOFFLOT, Manuel DEPREZ, Benaïssa EL MOUALIJ, Awad OSMAN, Jean-François THONNART, Olivier HOUGRAND, Ernst HEINEN, Willy ZORZI. Immuno-quantitative PCR for Prion Protein detection in Sporadic Creutzfeldt-Jakob Disease. Clinical chemistry. 2005 Sep;51(9):1605-1611. 6 Gofflot S, El Moualij B, Zorzi D, Melen L, Roels S, Quatpers D, Grassi J, Vanopdenbosch E, Heinen E, Zorzi W. Immuno-quantitative polymerase chain reaction for detection and quantitation of prion protein. J Immunoassay Immunochem. 2004;25(3):241-58. 7- Jean Barbeau, Benaïssa El Moualij, Ernst Heinen, Willy Zorzi . TRANSMISSION ET RéSISTANCE DES PRIONS : LA PRATIQUE DE LA MéDECINE DENTAIRE EN SERA T-ELLEAFFECTéE ? Journal de l'Ordre des dentistes du Québec Volume 43 Décembre 2006, 43(9) : 461-467. PATENTS: 1-
ElMoualij Benaïssa, Zorzi Willy, Zorzi Danièle, Heinen
Ernst, Melen Laurence, Detection method by PCR, WO0131056, 2001-05-03,
IqPCR using a chimeric DNA marker for amplification, WO0131056,
2001-05-03 ; EP1232283, 2002-08-21 ; DE60028233T, 2007-03-08. LIST OF MAIN RESEARCH GRANTS: 1-
Development of an highly sensitive immuno-detection methods for
prions proteins. 2000-2004. MEMBER OF SCIENTIFIC SOCIETIES Belgian
Society of Biochemistry and Molecular Biology (SBB). |
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President-elect of the Spanish Society of Biochemistry and Molecular Biology (SEBBM) and Full Professor of Biochemistry and Molecular Biology at the University of Seville. Instituto
de Bioquímica Vegetal y Fotosíntesis, Universidad
de Sevilla y CSIC, Avda. Américo Vespucio, 49 41092-Sevilla,
Spain Lecture Title: 'Protein Evolution and Geochemical Changes' |
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He is the founder and head of the Laboratory of Structural and Functional Proteomics, Institute of Plant Biochemistry and Photosynthesis, University of Seville and National Research Council (CSIC), Spain. His major research interests are in the structure-function relationships of metalloproteins, protein evolution, photosynthesis and bioenergetics. He is author or co-author of 4 books, 2 patents, and over 140 original articles and book chapters, and has been invited speaker in more than 100 scientific meetings. He is/has been member of the FEBS Advanced Courses Committee (2003-06) and of the IUBMB Nominating Committee (2003-06), former President (2003-07) and Secretary General (1996-2001) of the Bioelectrochemical Society, editor of FEBS Letters (2005-), associate editor of Bioelectrochemistry (2005-), President of the 22nd IUBMB & 37th FEBS Congress (Seville, 2012). Five Selected Publications (in the last few years): Photosynthesis:
A New Function for an Old Cytochrome? Electron
Transfer between Membrane Complexes and Soluble Proteins in Photosynthesis
(invited review). Structure
of the Complex between Plastocyanin and Cytochrome f from the
Cyanobacterium Nostoc Sp. PCC 7119 as Determined by Paramagnetic
NMR. Thermal
Unfolding of Plastocyanin from the Mesophilic Cyanobacterium Synechocystis
sp. PCC 6803 and Comparison with its Thermophilic Counterpart
from Phormidium laminosum. A
Proteomic Approach to Iron and Copper Homeostasis in Cyanobacteria
(invited review). |
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Prof. Vincent Pryde Kehdingha TITANJI Biotechnology Unit, University of Buea, Box 63, Buea, SW Province, Cameroon. E-mail: vpk.titanji@yahoo.com Lecture title: 'Molecular cloning and characterization of UB 05 a dominant antigen of Plasmodium falciparum with immune protective potential' |
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Prof. Vincent P.K. Titanji obtained his PhD degree (1978) and 'Docent' title (1988) in Physiological Chemistry from Uppsala University and his MSc degree in Animal Biochemistry from Lomonosov Moscow State University (1973). Subsequently, he founded and headed the Biotechnology Center, Nkolbisson, University of Yaounde I (1986-1992). He was appointed to the University of Buea as Dean of the Faculty of Science (1993-1998) Deputy Vice-Chancellor for Teaching(1998-2005) and Vice Chancellor since 2006. An expert in Protein Chemistry and Molecular Parasitology, he has devised diagnostic tests for river blindness, cloned vaccine candidates and identified new drug leads from medicinal plants for river blindness and malaria. He successfully trained 18 PhD graduates, 60 MSc students and has published widely in peer-reviewed journals. Prof. Titanji was instrumental in the creation of the Cameroon Biochemical Society and has been President and Secretary General respectively of the Federation of African Societies of Biochemistry and Molecular Biology (FASBMB) and the Federation of African Immunological Societies (FAIS). A Knight of the Cameroon Order of Valour, Prof. Titanji is a Chartered Biologist (C. Biol), and Fellow (FI Biol) of the Institute of Biology, London; a Fellow of the Third World Academy of Sciences (FTWAS) and a recipient of the IFS/DANIDA Prize. |
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Department of Biochemistry, Cell and Molecular Biology of Plants. Estación Experimental del Zaidín. Profesor Albareda, 1. 18008 Granada, Spain E-mail: matilde.baron@eez.csic.es Lecture Title:"Proteomic and imaging analysis of pathogen-challenged plants" ![]() |
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Current position: Since 2006 Research Scientist at the Department of Biochemistry and Molecular Biology of Plants, Estación Experimental del Zaidín (EEZ), Spanish Council of Scientific Research (CSIC), Granada, Spain. Graduated
in Biological Sciences, with Special Award from the UGR. University
of Granada (UGR, Spain) in 1978. Research Leader
of the group Response of the chloroplast against biotic and abiotic
stress. Selected publications M.
L. Pérez-Bueno, J. Rahoutei, C. Sajnani, I. García-
Luque and M. Barón. Abdelmalek
Hakmaoui, Matilde Barón, Mohammed Ater. L.
Chaerle, M. Pineda, D. Van Der Straeten, M. Barón M. L. Pérez-Bueno, M. Ciscato, M. vandeVen, I. García-Luque, R. Valcke, M. Barón. Imaging viral infection. Studies on Nicotiana benthamiana plants infected with the pepper mild mottle tobamovirus Photosynthesis Research, 90: 111-123, 2006. Carlota Sajnani, Jorge L. Zurita, Mercedes Roncel, José M. Ortega, Matilde Barón, Jean-Marc Ducruet. Changes in photosynthetic metabolism induced by tobamovirus infection in Nicotiana benthamiana studied in vivo by chlorophyll thermoluminescence. New Phytologist 175:120-130, 2007. Rodríguez-Moreno L., Pineda M., Soukupová J, Macho, A, Beuzón C.R., Barón M , Ramos C. Early detection of bean infection by pseudomonas syringae in asymptomatic leaf areas using chlorophyll fluorescence imaging. Phot. Res, 96:27-35, 2007. ( Mónica Pineda, László Gáspár, Fermín Morales, Zoltán Szigeti, Matilde Barón. Multi-colour fluorescence imaging: an useful tool to visualise compatible viral infection in plants (Photochemical Photobiology, 2008). Selected projects as project leader Supported
from the Spanish Research Agencies |
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Dominique
ROBY Directeur de Recherches CNRS. Leader of the group " Resistance, susceptibility and cell death in Arabidopsis thaliana in response to pathogenic bacteria " Institute : Laboratoire des Interactions Plantes/Microorganismes (LIPM), UMR INRA/CNRS 2594, Chemin de Borde Rouge, BP 52627, 31326 Castanet-Tolosan Cedex, France (toulouse.inra.fr). Tél. : 05 61 28 53 26, E-mail : dominique.roby@toulouse.inra.fr Lecture Title:'Key genes involved in resistance and hypersensitive cell death in Arabidopsis' ![]() |
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Director
of the Federative Institute of Research " Agrobiosciences,
Interactions and Biodiversity " of Toulouse Education
and Career History GODARD F., LUMMERZHEIM M., SAINDRENAN P., BALAGUE C. and ROBY D. (2000). Hxc-2, an Arabidopsis mutant with altered hypersensitive response to Xanthomonas campestris pv. campestris. Plant J. 24(6), 749-761 PONTIER D., BALAGUE C., BEZOMBES-MARION I., TRONCHET M., DESLANDES L. and ROBY D. (2001). Identification of a novel pathogen-responsive element in the promoter of the tobacco gene HSR203J, a molecular marker of the hypersensitive response. Plant J. 26(5), 495-509. VAILLEAU F., DANIEL X., TRONCHET M., MONTILLET JL., TRIANTAPHYLLIDES C. and ROBY D. (2002). A R2R3-MYB gene, AtMYB30, acts as a positive regulator of the hypersensitive cell death program in plants in response to pathogen attack. Proc. Natl. Acad. Sci. USA 99(15), 10179-10184.. BALAGUE C., LIN B., ALCON C., FLOTTES G., MALMSTROM S., KOHLER C., NEUHAUS G., PELLLETIER G., GAYMARD F. and ROBY D. (2003) HLM1, an essential component of signaling for the Hypersensitive Response, encodes a member of the CNGC ion channel family. The Plant Cell 15(2), 365- 379. LORRAIN S., VAILLEAU F., BALAGUE C. and ROBY D. (2003) Lesion mimic mutants : keys for deciphering cell death and defense pathways in plants ? Trends in Plant Sci. 8(6), 263- 271. LORRAIN S., LIN B., AURIAC M-C., KROJ, T., SAINDRENAN, P., NICOLE M., BALAGUE C. and ROBY D. (2004) VAD1, a novel GRAM domain-containing protein, is a regulator of cell death and defense responses in vascular tissues. The Plant Cell 16, 2217- 2232. JOURNOT-CATALINO N., SOMSSICH I., ROBY D. and KROJ T. (2006) The transcription factors WRKY11 and WRKY17 act as negative regulators of basal resistance in Arabidopsis thaliana. The Plant Cell 18, 1-14. PERCHEPIED L., KROJ T., TRONCHET M., LOUDET O. and ROBY D. (2006). Natural variation in partial resistance to Pseudomonas syringae is controlled by two major QTLs in Arabidopsis thaliana. PloS ONE 1(1): e123. doi:10.1371/journal.pone 0000123. RAFFAELE S., VAILLEAU F., LEGER A., JOUBES J., MIERSCHE O., HUARD C., BLEE E., MONGRAND S., DOMERGUE F. and ROBY D. (2008). A MYB Transcription Factor Regulates Very Long Chain Fatty Acid Biosynthesis for Activation of the Hypersensitive Cell Death in Arabidopsis. The Plant Cell (sous presse) Technological transfer and recent contracts Contrat
de Collaboration avec les sociétés Vilmorin Clause
& Cie, et Biogemma "Identification of new components
of resistance/cell death pathways through the search of interacting
partners of AtMYB30, a R2-R3 MYB transcriptional factor involved
in the regulation of the hypersensitive response in Arabidopsis",
2003-2006, 198,906 euros. |
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"Titular"
Professor at the University of Córdoba. Agricultural and
Plant Biochemistry and Proteomics, Department of Biochemistry
and Molecular Biology, Agricultural and Forestry High technical
School (escuelta Técnica Superior de Ingenieros Agrónomos
y de Montes) Lecture Title: 'Proteomics in the study of plant responses to biotic and abiotic stresses' |
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AREAS OF EXPERTISE/INTEREST Agricultural and Plant Biochemistry and Molecular Biology, Proteomics (plant proteomics, yeast proteomics), posttranslational modifications (redox proteome). Plant responses to biotic and abiotic stresses. Secondary metabolism (phenolics). GENERAL Head
of the Agricultural and Plant Biochemistry and Proteomics, University
of Córdoba FINNANCED RESEARCH PROJECTS (last 5 years, 2003-2008) Application of proteomics to the study of sunflower, an strategic crop for Argentina and Spain (Spanish AECI, Ministry of Foreign Affair) (A/014378/07), 2007-2009 Plant
proteomics in Europe" EUPP (European Plant Proteomics). EU.
European Cooperation in the field of Scientific and Technical
Research (COST) (OC-2006-217; FA 0603). 2006-2011.http://www.costfa0603.com/index.php. 1. Published papers 2004-2008 ( SCI Journals) Sira Ehevarría-Zomeño, David Ariza, Inmaculada Jorge, Christof Lenz, Jesús Jorrín, Rafael M Navarro Cerrillo. 2008. Changes in the protein profile of Quercus ilex leaves in response to drought-stress and and recovery. Journal of Plant Physiology (in press)
CASTILLEJO M.A., MALDONADO A..M, OGUETA S., JORRÍN, J. 2008. Proteomic analysis of responses to drought stress in sunflower (Helianthus annuus) by two-dimensional gel electrophoresis and mass spectrometry. The Open Proteomics Journal (in press) M.J. DUNN, C. GIL, C. KLEINHAMMER, F. LOTTSPEICH, S. PENNINGTON, J.-CH. SANCHEZ,J.P. ALBAR, L. BINI, F. CORRALES, G.L. CORTHALS, M.M. FOUNTOULAKIS, C. HOOGLAND, P. JAMES,O.N. JENSEN, C. JIMéNEZ, J. JORRÍN-NOVO, H.-J. KRAUS, H. MEYER, D. NOUKAKIS,P.M. PALAGI, D. PENQUE, A. QUINN, T. RABILLOUD. 2008. EuPA achieves visibility - An activity report on the first three years. Journal of Proteomics 1: 11-18. E. PRATS, J.C. GARCIA GALINDO, M. E. BAZZALO, A. LEÓN, F. A. MACIAS, D. RUBIALES, J. V. JORRÍN. 2007. Antifungal activity of constitutive phenolic compounds from capitulum of a head rot-resistant sunflower genotype. : Journal of Chemcal Ecology, in press ( DOI 10.1007/s10886-007-9388-9) JORRÍN, J., MALDONADO, A.M., CASTILEJO, MA. 2007. Plant proteome analysis: a 2006 update. Proteomics 7 2947 -2962 PéREZ-REINADO.E, RAMÍREZ-BOO.M, GARRIDO.J.J, JORRÍN.J.V AND MORENO.A. 2007. Toward global analysis of porcine alveolar macrophages proteins through two-dimensional electrophoresis and mass spectrometry. Developmental and Comparative Immunology 31: 1220-1232 E. PRATS, M. J. LLAMAS, J. JORRIN, AND D. RUBIALES. 2007. Constitutive Coumarin Accumulation on Sunfl ower Leaf Surface Prevents Rust Germ Tube Growth and Appressorium Diff erentiation. CROP SCIENCE,: 47: 1119-1124 RISPAIL.N, DITA M.-A, GONZÁLEZ-VERDEJO.C, PéREZ-DE-LUQUE.A, CASTILLEJO.M.-A, PRATS.E, ROMÁN.B, JORRÍN.J, RUBIALES.D. 2007. Plant resistance to parasitic plants: molecular approaches to an old foe. New Phytologist 173: 703-712. FERNÁNDEZ-ACERO.F.J, JORGE.I, CALVO.E, VALLEJO.I, CARBÚ.M, CAMAFEITA.E, GARRIDO.C, LÓPEZ.J.A, JORRIN.J AND CANTORAL.J.M. 2007. Proteomic analysis of phytopathogenic fungus Botrytis cinerea as a potential tool for identifying pathogenicity factors, therapeutic targets and for basic research. Archives of Microbiology 187: 207-215. ROLDÁN SERRANO.A, LUNA DEL CASTILLO.J, JORRÍN NOVO.J, FERNÁNDEZ OCAÑA.A, GÓMEZ RODRÍGUEZ.M.V. 2007. Chitinase and peroxidase activities in sunflower hypocotyls: effects of BTH and inoculation with Plasmopara halstedii. Biologia Plantarum 51: 149-152. ECHEVARRÍA-ZOMEÑO, S., PéREZ-DE-LUQUE, A., JORRÍN, J., MALDONADO, A.M. 2006. Pre-haustorial resistance to broomrape (Orobanche cumana) in sunflower (Helianthus annuus): cytochemical studies. Journal of Experimental Botany, 57:4189-420 ROSSIGNOL.M, PELTIER.JB, MOCK.H.P, MATROS.A, MALDONADO.A, JORRÍN.J. 2006. Plant proteome analysis: a 2004-2006 update. Proteomics 6:5529-5548. BÁRCENA JA, CALVETE JJ, MORENO-LOPEZ A, JORRÍN-NOVO JV. 2006. Editorial: out of Córdoba. Proteomics S1: 1-3- JORGE I, NAVARRO, RM, LENZ C, ARIZA D, JORRÍN J. 2006. Variation in the holm oak leaf proteome at different plant developmental stages, between provenances and in response to drought stress. Proteomics S1´06: 207-214. FERNÁNDEZ-ACERO FJ, JORGE I, CALVO E, VALLEJO I, CAMAFEITA LE, LÓPEZ JA, CANTORAL JM, JORRIN J. 2006. Two-dimensional electrophoresis protein profile of the phytopathogenic fungus Botrytis cinerea. Proteomics S1´06: 88-96. CURTO, M., CAMAFEITA, E., LOPEZ, J.A., MALDONADO, A.M., RUBIALES, D., JORRÍN, J.V. 2006. A proteomic approach to study pea (Pisum sativum) responses to powdery mildew (Erysiphe pisi). Proteomics S1´06: 163-174. JORRÍN, J.V., RUBIALES, D., DUMAS-GAUDOT, E., RECORBET, G., MALDONADO, A., CASTILLEJO, M.A., CURTO, M. 2006. Proteomics: a promising approach to study biotic stresses in legumes. A review. Euphytica 147: 37-47. PRATS.E., BAZALO.M.E., JORRÍN.J.V. 2006. Fungitoxic effect of scopolin and related coumarins on Sclerotinia sclerotiorum. A way to overcome sunflower head rot. Euphytica 147: 451-460. JORRÍN.J., BÁRCENA.J.A., CALVETE.J.J. 2005. Report on the First Congress of the Spanish Proteomics Society. Proteomics 5: 2712-2715. PéREZ DE LUQUE.A., JORRÍN.J.V., CUBERO.J.I, RUBIALES, D. 2005. Orobanche crenata resistance and avoidance in pea (Pisum spp.) operate at different developmental stages of the parasite. Weed Science 45: 379-387. JORGE, I., NAVARRO, M., LENZ, C., ARIZA, D., PORRAS, C., JORRÍN, J. 2005. . The Holm Oak leaf proteome. Analytical and biological variability in the protein expression level assessed by 2-DE and protein identification by MS/MS de novo sequencing and sequence similarity searching. Proteomics 5: 222-234. CÁNOVAS.M, DUMAS-GAUDOT, E., RECORBET, G., JORRÍN, J., MOCK, H.P., ROSSIGNOL, M. 2004. Plant proteome analysis. Proteomics 4: 285-298. CASTILLEJO, M.A., AMIOUR, N., DUMAS-GAUDOT, E., RUBIALES, D., JORRÍN, J.V. 2004. A proteomic approach to studying plant response to crenate broomrape (Orobanche crenata) in pea (Pisum sativum). Phytochemistry 65: 1817-1828. |
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Instituto de Biología Molecular y Celular de Plantas (IBMCP), Ciudad Politécnica de la Innovación, Universidad Politécnica de Valencia-CSIC, Camino de Vera s/n, 46022 Valencia, Spain. Tel. 34-96-3877883;
Fax 34-96-3877859 |
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Ramón Serrano is born at Valencia, Spain. He is Doctor Agricultural Enginneer, Research Professor of the spanish CSIC (Research Council) and Full Professor of Biochemistry and Molecular Biology at the Polytechnic University of Valencia, Spain. Condecorated
with the "Cruz de Alfonso X El Sabio" of the spanish
government and Doctor Honoris Causa by the University of Regensburg,
Germany. Naranjo,
M.A., Romero, C., Bellés, J.M., Montesinos, C., Vicente,
O. and Serrano, R. Yenush,
L., Merchan S, Holmes J, and Serrano R. Rubio,
S., Larson, T.R., Gonzalez-Guzman, M., Alejandro, S., Graham,
I.A., Serrano, R. Naranjo
MA, Forment J, Roldan M, Serrano R, Vicente O Alejandro
S, Rodriguez PL, Bellés JM, Yenush L, Garcia-Sanchez MJ,
Fernandez JA, Serrano R
Bueso,
E., Alejandro, S., Carbonell, P., Perez-Amador, M.A., Fayos, J.,
Bellés, J.M., Rodriguez, P.L. and Serrano, R. |
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Department
of Botany and Plant Sciences. Institute for Integrative Genome
Biology 2150 Batchelor Hall, University of California, USA Lecture Title: Small RNAs and epigenetic regulation in plant abiotic stress responses. |
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Education Professional
Experience Publications Synergistic
Activities Collaborators |
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Research
Professor of the Spanish Research Council (CSIC) Lecture Title: Arginine and Nitrogen Storage: a Structural View |
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Professor,
Doctoral Program, Biochemistry Dept., University of Valencia Education Research
and professional experience Appointments, Grants and Awards. Has been or is a member of Advisory Scientific Committees of the Fundación Valenciana de Investigaciones Biomedicas, of the Fundación de Investigación del Hospital "La Fe" (Valencia), and of Spanish granting bodies (Ministries of Health and of Education and Science), a Spanish representative to the standing Committee of the European Medical Research Council (EMRC, the medical branch of ESF), ad hoc grant reviewer for the NSF (USA) and ANEP (Spain), manuscript reviewer for several international scientific journals. Head investigator in 24 grants for research. Art/Sciences 2001 Award of the Valencian Community, and Cátedra Bernal Castejón Of the University of Zaragoza (2007). Research
interests and activity. His research is centered on studies of
the structure and function of enzymes of biomedical interest,
and of their complexes, having created a protein crystallography
unit in Valencia. He also studies the genetic and molecular bases
of inborn errors, particularly those affecting the urea cycle.
Ten
recent publications |
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Mohammed BAAZIZ |
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Scientific advisory Committee: -
1998 until 2006: Scientific Adviser for the International Foundation
for Sciences (IFS, Stockholm, Sweden). Awards - 1999: IFS Silver Jubilee Award, by the International Foundation for Sciences (IFS, Stockholm, Sweden. Titles Reviewer Member
of the editorial board: Publications for the last 5 years: - BOUDA, S., DEL CAMPO, F., HADDIOUI, A., BAAZIZ, M. & HERNÁNDEZ, E.E. 2008. RAPD and ITS-based variability revealed in Atriplex species introduced to semi-arid zones of Morocco. Scientia Horticulturae 118, 172-179. -MRABET,
A., FERCHICHI, A., CHAIRA, N., BEN SALAH, M., BAAZIZ, M. &
MRABET PENNY, T. 2008. Physico-chemical characteristics and
total quality of date palm varieties grown in the southern of
Tunisia. Pakistan Journal of Biological Sciences 11, 1003-1008. - QACIF, N., BAAZIZ, M. & BENDIAB, K. 2007. Biochemical investigations on peroxidase contents of male and female inflorescences of date palm (Phoenix dactylifera L.). Scientia Horticulturae 114, 298-301. - HADDIOUI, A. & BAAZIZ, M. 2006. Effect of salinity on seed germination and early growth of five natural populations of Atriplex halimus L. in Morocco ; Physiol. Mol. Biol. Plants 12, 247-251. -KHALES,
A. & BAAZIZ, M. 2005. Quantitative and qualitative aspects
of peroxidases extracted from cladodes of Opuntia ficus indica.
Scientia horticulturae 103, 209-218. -TAHLIL,
N., RADA, A., EL GHARMALI, A., BAAZIZ, M. & EL MERAY, M. 2003.
Use of peroxidase activity in leaves and roots of two varieties
of zucchini (Cucurbita pepo L.) as biomarkers of toxicity
of soil contaminated by the spread of urban wastes. Agrochimica
XLVII (3-4), 241-247. -AZEQOUR,
M., AMSSA, M. & BAAZIZ, M. 2002. Identification de la
variabilité intra-clonale des vitroplants de palmier dattier
issus de culture in vitro par organogenèse. Etude morphologique.
C. R. Biologies 325, 947-956. -MAJOURHAT, K., BENDIAB, K., MEDRAOUI, L. & BAAZIZ, M. 2002. Diversity of leaf peroxidases in date palm (Phoenix dactylifera L.) as revealed in an example of marginal (seedling-derived) palm groves. Scientia Horticulturae 95, 31-38. -AZEQOUR, M., MAJOURHAT, K. & BAAZIZ, M. 2002. Morphological variations and isoenzyme polymorphism of date palm clones from in vitro culture acclimatized and established on soil in south Morocoo. Euphytica 123, 57-66. |
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Assistant
Professor, Department of Plant Science, McGill University, Canada Lecture
Title:
'Plant-Insect Interactions: the Potential Role of Cross-Talk in |
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Research:
Plants adjust their defense responses to target herbivores. In response, insect herbivores have evolved adaptive strategies to undermine these plant defenses. Research in Bede's laboratory lies at the boundary of plant-caterpillar interactions, characterizing the co-adaptive responses between plant and caterpillar herbivores at the molecular, biochemical and physiological levels. Understanding the underpinnings of these complex interactions is critical to gain insight into the complex molecular evolution between plants and insects and develop effective pest management strategies. Selected
publications: Babic, B, Poisson, A, Darwish, S, Lacasse, J, Merkx-Jacques, M, Despland, E and Bede, JC. 2008. Influence of dietary nutritional composition on caterpillar salivary enzyme activity. Journal of Insect Physiology. 54: 286-296. Merkx-Jacques, M, Despland, E and Bede, JC. 2008. Nutrient utilization by generalist caterpillars of the beet armyworm, Spodoptera exigua. Physiological Entomology. 33: 51-61. Darwish, S, Pan, L, Ide, C, Bede JC. 2008. Caterpillar-specific gene expression in Medicago trucatula. Plant Molecular Biology Reporter 26: 12-31. Bede, JC, McNeil, JN, Tobe, SS. 2007. The role of neuropeptides in caterpillar nutritional ecology. Peptides 28:185-186 Bede, JC, Musser, RO, Felton, GW and Korth, KL. 2006. Caterpillar herbivory and salivary enzymes decrease transcript levels of Medicago truncatula genes encoding early enzymes in terpenoid biosynthesis. Plant Molecular Biology 60: 519-530 Merkx-Jacques, M and Bede, JC. 2005. Influence of diet on larval Spodoptera exigua glucose oxidase activity. Journal Insect Science 5: 48. Gomez, SK, Cox, MM, Bede, JC, Inoue, K, Alborn, HT, Tumlinson, JH and Korth, KL 2005. Lepidopteran herbivory and oral factors induce transcripts encoding novel terpene synthases in Medicago truncatula. Arch. Insect Biochem. Physiol. 58:114-127. |
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"Catedrático"
(Full Professor), Dept. Biochemistry and Molecular Biology, Autonomous
University of Barcelona. Dept. Bioquímica, Fac. Veterinaria,
Universitat Autònoma de Barcelona, Bellaterra, Barcelona
08193, Spain Lecture Title: 'Unraveling cation homoestasis in yeast: a model for plant stress adaptation' |
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1986. Ph.D. in Biochemistry (University of Barcelona) Academic
Positions Research interests 1.- Regulation of biological processes by phospho-dephosphorylation mechanisms (mainly Ser/Thr protein phosphatases) 2.- Response to stress in yeast (saline, osmotic, oxidative, alkaline). 3.- Gene regulation and genome-wide transcriptional analysis. Publications (Last 5 years) (Around 90 articles or reviews in international research journals. Publication listed below correspond to those appeared in the last 5 years) - Ruiz, A., Serrano, R., & Ariño, J. (2008) Direct regulation of genes involved in glucose utilization by the calcium/calcineurin pathway. J. Biol. Chem. 283, 13923-33. - Moreno-Romero, J., Espunya, M. C. Platara, M., Ariño, J. & Martínez M. C. (2008) A role for protein kinase CK2 in cell division in the context of Arabidopsis thaliana development: evidence using a dominant negative mutant. Plant Journal 55, 118-130. - González, A., Larroy, C., Biosca, J.A. & Ariño, J. (2008) The use of the TRP1 auxotrophic marker for gene disruption and phenotypic analysis in yeast: a note of warning. FEMS Yeast Research 8, 2-5. - Menacho-Marquez, M., Perez-Valle, J. Ariño, J., Gadea, J. & Murguia JR (2007) Gcn2p regulates a G1/S cell cycle checkpoint in response to DNA damage. Cell Cycle 6, 2302 - 2305. - Pagani, M.A., Casamayor, A., Serrano, R., Atrian, S. & Ariño, J. (2007) Disruption of iron homeostasis in Saccharomyces cerevisiae by high zinc levels: a genome-wide study. Mol. Microbiol. 65, 521-537. - Aksenova, A., Muñoz, I., Volkov, K., Ariño, J. & Mironova, L. (2007) The Hal3-Ppz1 dependent regulation of nonsense suppression efficiency in yeast and its influence on manifestation of the yeast prion-like determinant [isp+]. Genes to Cells, 12 435-445. - Pedelini, L., Marquina, M., Ariño, J., Casamayor, A., Sanz, L., Bollen, M., Sanz, P. & Garcia-Gimeno, M.A. (2007) Ypi1 and Sds22 regulate the nuclear localization and function of yeast type 1 phosphatase Glc7. J. Biol. Chem. 282, 3282-3292. - Serrano, R., Martín, H., Casamayor, A. & Ariño, J. (2006) Signalling alkaline pH stress in the yeast Saccharomyces cerevisiae through the Wsc1 cell surface sensor and the Slt2 MAP kinase pathway. J. Biol. Chem. 281, 39785-39795. - Platara, M., Ruiz, A., Serrano, R., Palomino, A., Moreno, F. & Ariño, J. (2006). The transcriptional response of the yeast Na+-ATPase ENA1 gene to alkaline stress involves three main signaling pathways. J. Biol. Chem. 281, 36632-36642. - González, A., Ruiz, A., Serrano, R., Ariño, J. & Casamayor, A. (2006) Transcriptional profiling of the protein phosphatase 2C family in yeast provides insights into the unique functional roles of Ptc1. J. Biol. Chem. 281, 35057-35069. - Ruiz, A., González, A., García-Salcedo, R., Ramos, J. & Ariño, J. (2006) Role of protein phosphatases 2C on tolerance to lithium toxicity in the yeast Saccharomyces cerevisiae. Mol. Microbiol. 62, 263-277. - García-Salcedo, R., Casamayor, A., Ruiz, A., González, A., Prista, C., Loureiro-Dias, M.C., Ramos, J. & Ariño, J. (2006) Heterologous expression implicates a GATA factor in regulation of nitrogen metabolic genes and ion homeostasis in the halotolerant yeast Debaryomyces hansenii. Eukaryotic Cell. 5, 1388-1398. - Ruiz, A., Ruiz, M.A., Sánchez-Garrido, M.A., Ariño, J. & Ramos, J. (2004) The Ppz protein phosphatases regulate Trk-independent potassium influx in yeast. FEBS Lett. 578, 58-62. - Muñoz, I., Ruiz, A., Marquina, M., Barceló, A., Albert, A., & Ariño, J. (2004) Functional Characterization of the Yeast Ppz1 Phosphatase Inhibitory Subunit Hal3. A Mutagenesis Study. J. Biol. Chem. 279, 42619-42627. - Alberola, T.M., García-Martínez, J., Antúnez, O., Viladevall, L., Barceló, A., Ariño, J. & Pérez-Ortín, J.E. (2004) A new set of DNA macrochips for the yeast Saccharomyces cerevisiae: features and uses. Intl. Microbiol. 7, 199-206. - Bernal, D., Serrano, R., Simón, E. & Ariño, J. (2004) Copper and iron are the limiting factors for growth of the yeast S. cerevisiae in an alkaline environment. J. Biol. Chem. 279: 19698 - 19704. - Ruiz, A., Muñoz, I., Serrano, R., González, A., Simón, E. & Ariño, J. (2004) Functional characterization of the Saccharomyces cerevisiae VHS3 gene. A regulatory subunit of the Ppz1 protein phosphatase with novel, phosphatase-unrelated functions. J. Biol. Chem. 279, 34421-34430. - Viladevall, L., Serrano, R., Ruiz, A., Doménech, G., Giraldo, J., Barceló, A., & Ariño, J. (2004) Characterization of the calcium-mediated response to alkaline stress in Saccharomyces cerevisiae. J. Biol. Chem. 279, 43614-43624. Reviews & Book Chapters - Ariño, J.; Posas, F & Clotet, J. (1998) Isolation, characterization and function of novel Ser/Thr protein phosphatases in yeast. In: Methods in Molecular Biology: Protein Phosphatase Protocols. Vol 93, pp. 305 313. (J.W. Ludlow, Ed.) Humana Press, NJ.
- Pujol, G.; Ferrer, A. & Ariño, J.(1998) Protein Phosphatases
2A and protein Phosphatase X genes in Arabidopsis thaliana. In:
Methods in Molecular Biology: Protein Phosphatase Protocols. Vol
93, pp. 201-212. (J.W. Ludlow, Ed.) Humana Press, NJ. -
Clotet, J. & Ariño, J. (2000) Nuevos componentes de
la regulación del ciclo celular. Investigación y
Ciencia. Octubre. Pp. 36-37. -
Ariño, J. (2002) Novel protein phosphatases in the yeast:
an update. Eur. J. Biochem. 269, 1072-1077. -
Ariño, J. & Herrero, E. (2003) Use of tetracycline-regulatable
promoters for functional analysis of protein phosphatases in yeast.
Methods in Enzymology. 366, 347-358. -
Protein Phosphatases. (2004) In: Current Topics in Genetics. (J.
Ariño and D. Alexander Eds.) Springer-Verlag, Berlin. -
Ariño, J., Casamayor, A., Ruiz, A., Muñoz, I., Marquina,
M. (2007) The use of yeast genetic tools to define biological
roles of novel protein phosphatases. In: Protein Phosphatase Protocols.
Methods in Molecular Biology, vol. 365, pp. 299-308. (G. Moorhead,
Ed.) Humana Press, NJ. (1-58829-711-X ) - Ruiz, A. & Ariño, J. (2007) Function and Regulation of the Saccharomyces cerevisiae ENA Sodium ATPase System. Eukaryotic Cell 6, 2175-83. Other relevant information -
Head of the DNA Microarray and Sequencing Facility at the Autonomous
University of Barcelona. |